In a discussion on the persistence with which attempts to dislodge the colon bacillus from the urinary tract are defeated, Barborka reminded me that the urine of patients who are receiving a diet high in fat and low in carbohydrate is considerably acidified. Shohl and Janney,1 a number of years ago, demonstrated that growth of colon bacilli was inhibited in urine of which the acidity was as great as pH 4.6 or 5.0, or alkalinity as much as pH 9.2 or 9.6.
In October, I2 reported the results in two cases of bacilluria of Escherichia coli type, in which the ketogenic diet was given. Since that time, the treatment has been applied in several additional cases of persistent bacilluria, and the patients have been under observation long enough to allow the results to be evaluated.
In the accompanying table is a summary. Several notable features emerged
CLARK AL. BACILLURIA UNDER KETOGENIC TREATMENT. JAMA. 1932;98(20):1710-1711. doi:10.1001/jama.1932.02730460014005