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Tuberculin Tests in Children Vaccinated with B C G
In a recently published article, Dr. A. de Carvalho of Rio de Janeiro reports on 723 intradermal reactions with large doses of tuberculin (up to 1 mg.) in 661 infants, from birth up to the age of 36 months, who had previously received the B C G vaccine by oral administration, in order to determine the presence of allergy to tuberculin in those infants. The general results confirmed the previous experience of the author. The reactions gave positive results in 582 tests (80.5 per cent); the results were negative in 119 tests (16.4 per cent), and there were doubtful results in 22 tests (3.1 per cent). The positive reactions seemed to be caused by the action of the B C G bacillus, because they occurred in vaccinated infants who did not live in a tuberculous environment. In the group of infants
RIO DE JANEIRO. JAMA. 1932;98(20):1758. doi:10.1001/jama.1932.02730460062028