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February 12, 1938

The Physiology of the Kidney

JAMA. 1938;110(7):533. doi:10.1001/jama.1938.02790070057030

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This book constitutes a clear and concise presentation and interpretation of the extensive literature, pertaining to the excretory function of the kidney, that has accumulated since 1920. An admittedly incomplete bibliography of some 497 references is included. In the introduction the author points out that the constancy of the internal environment is to a large extent dependent on the activity of the kidneys. A precise description of the nephron is followed by a simple exposition of the theories of renal excretion. The recent evidence pertaining to glomerular filtration and tubular reabsorption and excretion in different animals is then summarized. The remaining seven chapters of part 1 of the book are devoted to a discussion of the renal clearance. This discussion with its critical interpretations may be considered to be the most valuable portion of the book by those interested in the evaluation of tests of renal function. In the final

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