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February 12, 1938

Practical Endocrinology: Symptoms and Treatment

JAMA. 1938;110(7):534. doi:10.1001/jama.1938.02790070058033

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The first edition of this book was reviewed in The Journal, Aug. 24, 1935. The serious deficiencies pointed out at that time unfortunately still apply to the revised version. Changes have been limited to minor additions and deletions in the text, without repagination (but with the insertion of one extra page) and the addition of a fourteen page supplement. Bold face numbers inserted in the text refer to sections of the supplement. This review is concerned chiefly with the new material.

The author implies that estrone (theelin) is less properly given orally than estradiol (which he erroneously designates "estrandiol," a different compound) or estriol (theelol). The available evidence indicates that estrone and products (such as amniotin) containing it are quite active orally. He recommends the use of dinitrophenol and dinitrocresol in the treatment of obesity and claims that he has yet to see his "first seriously undesirable reaction" in over

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