In 1932 Ginzburg and Oppenheimer1 presented their studies of fifty-two cases of nonspecific inflammation of the bowel which had been observed in the previous ten years. An accurate etiologic or pathologic classification of this material was not possible. However, they submitted a classification, "fully conscious of its defects and overlappings but pleading in its favor a certain degree of clinical utility."
One group of fourteen cases presented pathologically a localized chronic nonspecific hypertrophic ulcerative stenosing inflammatory lesion of the terminal ileum, which was sometimes associated with fistula formation. This group, called "regional ileitis," was emphasized in a separate publication with Crohn2 because of certain typical additional clinical and radiologic features. In the original communication,1a illustrative cases were cited. One of the cases of ileitis (case 10) has presented an interesting course since the initial radical operation. Since our knowledge of the ultimate outcome of these patients following
Oppenheimer GD. RECURRENT OR RESIDUAL PROGRESSIVE ILEITIS. JAMA. 1938;110(14):1103–1104. doi:10.1001/jama.1938.62790140006008c