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To the Editor:—
Regarding the article on the "Therapy of Icterus (Jaundice)" (The Journal, March 5, p. 732) I believe that section E, paragraph 3, of treatment, in which it is stated regarding the use of intravenous dextrose that it must be given intravenously as then the glycogen is deposited in the liver more liberally than when the sugar is taken by mouth, should be changed to:In patients who cannot take oral dextrose because of vomiting or drowsiness it must be given intravenously, but in patients who can take and retain dextrose by mouth it should be given orally, since this method is simpler and more convenient. The glycogen deposit in the liver is practically the same in the two methods.This suggestion is advanced on the basis of Althausen's paper on "Deposition of Glycogen in Normal and in Experimentally Damaged Livers After Oral and Intravenous Administration of Dextrose"
White FW. THERAPY OF JAUNDICE. JAMA. 1938;110(22):1853. doi:10.1001/jama.1938.02790220055024