Replacement of renal parenchyma by fatty tissue has been until recently regarded as a rare condition, as a specific type of process resulting from infection and as limited almost entirely to the so-called surgical diseases of the kidney. Mention of this disease in the literature has been infrequent, and the confusion as to its cause is indicated by the profusion of titles given it. These include fatty transformation of the kidney, fatty degeneration of the kidney, lipomatosis renis, substitutio renis adiposa, lipomatous paranephritis, lipoma- tous nephritis, lipome intranephritic and degeneration lipoma. The main purpose of this paper is at once to clarify, simplify and enlarge the concept of this particular entity.
In the early literature replacement lipomatosis was at times confused with true lipoma of the kidney, a condition which is quite rare. Elansky1 quoted Lubarsch as saying that in 40,000 autopsies only one lipoma was observed in the
ROTH LJ, DAVIDSON HB. FIBROUS AND FATTY REPLACEMENT OF RENAL PARENCHYMA. JAMA. 1938;111(3):233–239. doi:10.1001/jama.1938.02790290019006