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September 17, 1938


JAMA. 1938;111(12):1123-1124. doi:10.1001/jama.1938.02790380065026

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To the Editor:—  In the Paris letters March 12 and June 25, published respectively in The Journal April 9 and July 23, appeared reports under the title "The Intensive Treatment of Syphilis." These reports emanated from Dr. Arnault Tzanch and Dr. Paul Chevallier. These authors are using massive doses of arsphenamine in the treatment of syphilis, using the drip method. One death is reported in their series. My purpose in this communication is to call attention to two points:1. No mention is made by these authors of my prior work done in association with Dr. Louis Chargin and Dr. William Leifer (The Application of the Intravenous Drip Method to Chemotherapy as Illustrated by Massive Doses of Arsphenamine in the Treatment of Early Syphilis, The Journal, March 16, 1935, pp. 878-883). This is the more curious since in the official journal of the hospitals of Paris (La sémaine des Hôpitaux

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