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The preface to Dr. Parker's book expresses conservatively the fact that methods of tissue culture have been well standardized and brought down to date in Dr. Carrel's laboratory in the Rockefeller Institute for Medical Research. These methods may be applied in "five major fields of investigation, namely experimental morphology and the study of tumors, viruses, hypersensitivity and immunity." The introduction by Dr. Carrel is an excellent review of the facts pertaining to the origin, purposes, difficulties and possibilities of this method of research as one of the aids in transforming a dry, dead morphologic concept of life into one dominated by biologic and physical reactions. It is quite evident in Dr. Carrel's review that fresh tissue culture, as a method of study, is still in experimental stages, requiring refinement of technic, carefulness of controlled observation and conservatism in interpretation and clinical application. The body of the book is particularly devoted
Methods of Tissue Culture. JAMA. 1938;111(12):1131. doi:10.1001/jama.1938.02790380073039