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September 24, 1938


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JAMA. 1938;111(13):1153-1156. doi:10.1001/jama.1938.02790390009003

The relationship between pregnancy and tuberculosis has been a topic of interest to physicians and their patients for centuries. In the old writings one finds repeated expression of the notion that sterility may be a factor in the pathogenesis of consumption. Pregnancy was prescribed, therefore, for its prevention or treatment. "Among those who have entertained the opinion that pregnancy impedes the march of phthisis may be mentioned Rokitansky, Clark, Williams, Andral, Warren, and, indeed a large majority of observers, up to the close of the last century."1

The converse doctrine that conception, pregnancy, parturition and lactation, together or singly, once or repeated, may be responsible for the breakdown was later asserted. Grisolle maintained that "pregnancy manifests a marked injurious influence over the progress of phthisis while accouchement and the puerperal state fail to exert any prejudicial influence over the march of the pulmonary disease; but, on the contrary, the

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