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September 24, 1938

HYPERTENSION IN A PATIENT WITH A SOLITARY ISCHEMIC KIDNEY

Author Affiliations

CHICAGO

From the Department of Medicine and the Department of Pathology of the University of Chicago.

JAMA. 1938;111(13):1159-1162. doi:10.1001/jama.1938.02790390015005
Abstract

Goldblatt1 and others have shown that hypertension develops in dogs and in monkeys when one kidney is made ischemic by partially clamping its artery. The hypertension is more readily produced when one kidney is first removed. This case is reported because of its bearing on previous work and because no analogous case has been found in the literature.

REPORT OF CASE 

History.—  A man aged 57, who first came to the University of Chicago Clinics July 27, 1937, had pneumonia at the age of 30 but was otherwise well until December 1935, when he fell down a flight of stairs. The same day the right kidney was removed because of laceration. Histologic preparations of the removed kidney showed no pathologic changes except massive hemorrhage at the site of laceration (fig. 1). After the operation thrombophlebitis developed in the legs, but otherwise the patient recovered without difficulty.He was well

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