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To the Editor:—
In a recent issue of The Journal (August 13, p. 605) Sabin reported that poliomyelitis was produced when he injected the virus in the tonsillopharyngeal area of Macacus rhesus monkeys. He indicated that after tonsillopharyngeal injection the virus probably progressed along peripheral nerves to the bulbar nuclei, thereby producing bulbar palsy.That virus can spread along nerves of the upper part of the gastrointestinal tract to the medullary area has been demonstrated in our laboratory. How bulbar palsy might develop in the human being has been previously discussed (Toomey, J. A.: Poliomyelitis, Am. J. Dis. Child.50:1362 [Dec.] 1935). The possible pathways of infection from the gastrointestinal tract, including the one from the glossopharyngeal area, were outlined in a recent publication (Toomey, J. A.: Round Table Discussion on Poliomyelitis, J. Pediat. 7:279 [Aug.] 1935, fig. 1). When the isolated seventh nerve (Toomey, J. A.: The
Toomey JA. SPREAD OF THE VIRUS OF POLIOMYELITIS. JAMA. 1938;111(13):1230. doi:10.1001/jama.1938.02790390086026