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October 15, 1938

THE ROLE OF THE ADRENALS IN HYPERTENSION

Author Affiliations

University of Chicago, Chicago.

JAMA. 1938;111(16):1491. doi:10.1001/jama.1938.02790420071024

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Abstract

To the Editor:—  In The Journal, August 6, page 556, appeared a communication from W. B. Cannon concerning an article by Rogoff and Marcus entitled "The Supposed Role of the Adrenals in Hypertension," which was published in The Journal, June 25. Dr. Cannon has published articles with similar content and manifesting a similar personal attitude on previous occasions (e. g. Endokrinologie6:24 [Jan.] 1930; Pharos of A. O. A., May 1938).Dr. Cannon has challenged our statements on which we base argument for serious deprecation of certain risky clinical procedures that can be justified by his so-called emergency theory. He objects to our criticism of the suggestion admittedly made by him (Am. J. Physiol.27:64, 1911) "that hypertension might be dependent on adrenal secretion and that adrenal secretion might be continuously stimulated by circulating epinephrine." Furthermore, he is evidently concerned because we did not refer to certain of

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