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October 22, 1938

Typhoid Fever on the Witwatersrand: Bacteriological Aspects, Serological Diagnosis, Specific Prophylaxis and Specific Treatment

JAMA. 1938;111(17):1589. doi:10.1001/jama.1938.02790430073029

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Abstract

The observations recorded in this monograph are considered under four headings noted in the title. The work which forms the basis of the report was carried out among native mine workers in an area where' typhoid is widely prevalent. As the author states, the workers lived under "herd" conditions. Food was served to several thousand from one kitchen. The sewage disposal was crude, the bucket system being used underground. The miners were largely non-Europeans, who worked in the mines an average of nine months, thereafter returning to their native "kraal." Some 300,000 men were thus employed, among whom the carrier rate was 2 per cent.

The section on bacteriologic aspects deals largely with strains isolated from blood and excreta, classified according to the method of Kaufman. The majority of strains were found to belong in Kaufman's V-W group, containing Vi antigen. The V type with a preponderance of Vi antigen

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