Preservation of tissue and function is seldom considered with greater care in the treatment of cancer than for growths on the eyelids. By the present methods of radiation therapy cancer in this location may be destroyed with minimum loss of normal tissue and consequently without deformity other than that caused previously by the growth itself.
From 1932 to 1937 inclusive, sixty-two consecutive patients with cancer of the eyelids were treated. Positive results from biopsy were obtained for forty-eight patients, and only this group will be considered in this discussion.
Chronic irritation is an important inciting factor for the majority of cancers of the eyelids. A local causative factor, namely eyeglasses, was demonstrated definitely with fourteen patients. The nose piece, either ill fitting or worn and rough, was a factor with eight patients, since the growth started in the depression or on the margin made by the guard. Pressure of
SHARP GS. THE TREATMENT OF CANCER OF THE EYELIDS. JAMA. 1938;111(18):1617-1622. doi:10.1001/jama.1938.02790440011003