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October 29, 1938

Die "postvaccinale Encephalitis" nach amtlichen österreichischen Daten

JAMA. 1938;111(18):1687. doi:10.1001/jama.1938.02790440081025

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This monograph is crowded with interesting epidemiologic and clinical observations. In 1801 and 1802 the official reports for Bohemia listed in a series of 10,090 vaccinations thirty-five cases of a central nervous system disease which today would be diagnosed as postvaccinal encephalitis. Between 1925 and 1935 240 cases of this complication with a mortality of seventy-three (30.4 per cent) were diagnosed in Austria. Although the malady had reached a low level in England and the Netherlands, forty cases were seen in 1933. It is noteworthy that the susceptibility for this complication is low during the first five years of life despite the large number of vaccinations. It reached its highest incidence in the age groups 7 to 9. A greater liability of the females is shown in the relationship of 113 males to 127 females. A seasonal predominance during May to July with a peculiar regional frequency for example in

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