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November 12, 1938

Le traitement de la tuberculose pulmonaire par la tuberculine

JAMA. 1938;111(20):1872. doi:10.1001/jama.1938.02790460066024

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This paper covered monograph in French summarizes Jaquerod's experiences and views on tuberculin therapy in general and particularly in pulmonary tuberculosis. His experiences date back as far as 1903 and were reported variously in 1905, 1909, 1912 and 1920 in the Revue médicale de la Suisse Romande. In the introduction he notes that viable bacilli and tuberculins (old tuberculin and bacillus emulsion) differ in action and briefly reviews the tuberculin treatment of pulmonary tuberculosis. The nature of tuberculin (old tuberculin and bacillus emulsion) and its toxic action is detailed, as well as the therapeutic action based on the conception of a toxic tuberculin reaction (the focal reaction) and an antituberculin immunization. Contraindications in certain types of tuberculosis, such as the danger of focal reactions in intestinal tuberculosis, are pointed out. In well chosen clinical cases, tuberculin treatment has a place, he believes. He employs it, beginning with very small but

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