J. E. M., a white man aged 51, was admitted to the Jefferson Hospital in March 1931, acutely ill with hemophilia. He presented signs and symptoms pointing to the presence of hemorrhage in the meninges, pleural cavities and abdominal viscera. There was bleeding from the genito-urinary tract, and there were also many large areas of subcutaneous hemorrhages.
After several days the patient was worse and in what seemed a hopeless condition; feeling that possibly these hemorrhagic crises were an effort of nature for relief, my associates and I1 tried venesection. The results were surprising. Though the patient had been in a comatose condition, forty-eight hours after the venesection he was clear mentally and seemed in good shape physically. Since that time, a period of seven years, he has been constantly under the care of one of us (A. B. G.) and has had venesection done, with the removal of
Lawson GB, Graybeal AB. HEMOPHILIA TREATED BY VENESECTION. JAMA. 1938;111(23):2104-2105. doi:10.1001/jama.1938.72790490002008a