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December 3, 1938

La syphilis du système nerveux: Pathologie générale, thérapeutique et prophylaxie

JAMA. 1938;111(23):2143. doi:10.1001/jama.1938.02790490073033

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This is written in simple and concise language and is mainly the result of the author's rich experience in the past thirty years. It is divided into five parts. The first part discusses spinal fluid examinations and syphilitic meningitis. The second part discusses possible etiologic factors such as neurotropic virus, environment and the role of treatment in late nervous complications. The third part concerns itself with pathogenesis of the two great classes of nervous disorders, mainly vascular and parenchymatous nervous syphilis, and is well treated. The fourth part deals with treatment and includes drugs, treatments of specific entities and complications. The fifth part deals with prophylaxis of syphilis of the nervous system. The laboratory examinations receive adequate discussion. Illustrations are easy to understand, being semidiagrammatic. In the treatment the value of neoarsphenamine and bismuth compounds is generally recognized, especially in the prophylaxis of nervous syphilis. In the specific treatment of

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