[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.145.213.148. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Other Articles
January 28, 1939

METRAZOL THERAPY IN SCHIZOPHRENIAREPORT OF A FATAL CASE WITH AUTOPSY

Author Affiliations

Sykesville, Md.

JAMA. 1939;112(4):310-311. doi:10.1001/jama.1939.62800040003008b
Abstract

There has been much enthusiasm recently for metrazol therapy of the functional psychoses. This is based on the dramatic remissions, on its ease of administration and on its adaptability to the treatment of large groups of patients. The literature, however, is still too meager to acquaint one with all the potential dangers attendant on the treatment. Meduna has treated more than 400 patients without a single death; in all, upward of 1,500 patients must have received metrazol therapy.1 Severe headache, nausea and vomiting, fractures and dislocations, and many minor complications are common, but to date only three fatal cases have been reported. We record in detail, with autopsy, a case under metrazol therapy which terminated fatally.

REPORT OF CASE 

History.—  D. G., a white man aged 24, since June 1936 had complained of nervousness, weakness, trembling, pains in the head, back and abdomen and a subjective sensation of

First Page Preview View Large
First page PDF preview
First page PDF preview
×