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March 2, 1946

RUBELLA IN PREGNANCY CAUSING MALFORMATIONS IN NEWBORN

Author Affiliations

Milwaukee

From the South View Hospital of the Milwaukee Health Department and the Department of Medicine, Marquette University School of Medicine.

JAMA. 1946;130(9):568-569. doi:10.1001/jama.1946.02870090022007
Abstract

Investigation is being directed at the present time to congenital malformations of the newborn of mothers having had rubella during pregnancy. The congenital anomalies noted have been cataracts, heart disease, deafmutism, microcephaly, microphthalmos, atresia of the biliary ducts and renal glomerulosclerosis.

Table 1 presents most of the authors and their publications.

Gregg1 in 1941 reported a series of 78 cases of congenital cataracts occurring in the children of mothers who had rubella from 1939 to 1941. Swan2 investigated the problem by examination of congenitally defective children and subsequent corroboration of the rubella complication by an interview with the mothers. Swan3 later reported further observations of rubella during pregnancy with its sequelae of congenital defects in the child. Carruthers4 reported a high incidence of deaf-mutism, with a classification of the type, in his

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