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Immunization Against Infections Due to a Filtrable Virus
Mr. Lignières, a former student at the Pasteur Institute, who was sent to Buenos Aires to organize the bacteriologic and veterinary services of the Argentine government, has been doing research work for a long time with a view to elaborating a general method of vaccination against diseases due to a filtrable virus. The work is beset with many difficulties. Vaccination against foot and mouth disease, swine plague and cattle plague can be accomplished by injecting simultaneously under the skin (but in different parts of the body) a therapeutic serum of the disease and a minimum quantity of its virus. This method, which has the advantage of conferring a marked immunity and of being applicable at a single sitting, is not devoid of danger if it is employed in regions that are exempt, because it creates veritable foci of infection, particularly if vaccination
PARIS. JAMA. 1932;99(13):1095-1096. doi:10.1001/jama.1932.02740650053022