In the male, pain in the left lower quadrant, with nausea or vomiting, predicates diverticulitis of the sigmoid; in the female, in whom this disease is of relative infrequency, it may mean any one of numerous diseases.
Since 1919 I have operated on seventy-one patients for acute diverticulitis, of whom fifty-six were males and fifteen were females. Carnial stated that there are two or three cases in the male to every case in the female. Of my series, several patients had had multiple attacks. One had had two distinct perforations during a period of thirteen or more years, for each of which he was operated on; the others had had two attacks, for which they had been operated on. The gangrenous perforations in each patient were in demonstrably different areas.
I1 called attention in 1918 to the possibilities of repeated attacks. My associate at that time, Dr. Thomas Russell,
ERDMANN JF. DIVERTICULITIS AND DIVERTICULOSIS. JAMA. 1932;99(14):1125–1128. doi:10.1001/jama.1932.02740660003001