Previous publications from our laboratory have mentioned the use of bacteriophage as an aid in the treatment of infections of the blood stream and we have indicated that in some instances the patients survived. So far we have not presented detailed information concerning any of these patients. It seems worth while to discuss some of these in considerable detail in order that the method of using bacteriophage may be more fully understood.
There are in the literature reports of bacteriophage treatment in small numbers of cases of blood stream infection. Little attention, however, has been given to the question of dosage and methods of administration. Obviously, a fairly large series of observations will be necessary before one can be very certain about the best technic.
For our present report there are available detailed hospital records on eight patients suffering from staphylococcus infection of the blood stream observed by us at
MacNEAL WJ, FRISBEE FC. BACTERIOPHAGE AS A THERAPEUTIC AGENT IN STAPHYLOCOCCUS BACTEREMIA. JAMA. 1932;99(14):1150–1155. doi:10.1001/jama.1932.02740660028007