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March 30, 1946


JAMA. 1946;130(13):894. doi:10.1001/jama.1946.02870130068021

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To the Editor:—  Crossman and Allen (The Journal, January 26, p. 185) in their remarks on shock state that it has been proved that isotonic solution of sodium chloride is equal or superior to plasma in the treatment of shock. Crossman in his further discussion of his article states that "great numbers of lives and limbs were unquestionably sacrificed by the official adherence to... pure plasma infusions." Such statements, based on animal experimentation, are directly contrary to the overwhelming clinical experience of military and civilian physicians and are impossible to reconcile with the proved beneficial results of hundreds of thousands of plasma infusions. My recent service in the army was intimately connected with the production of both plasma and whole blood. I am aware of no basis of fact for Dr. Crossman's remarks.The specific aim of the treatment of shock is the restoration of an adequate blood circulation to

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