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June 6, 1953


JAMA. 1953;152(6):532-533. doi:10.1001/jama.1953.03690060048015

For some years there has been an interest in the possibility of using "jet injections" as a method for the parenteral administration of drugs. In this procedure, no needle is used, the fluid to be injected being forced through the skin as a fine spray under high pressure by means of a special perforated syringe. Among the several advantages claimed for this procedure is a more uniform rate of absorption than is possible with the conventional method of intramuscular or subcutaneous injection. This is particularly important when it is desired to measure rate of utilization, storage, or excretion in diagnostic procedures. A recent report1 describes the use of a jet injector (Hypospray) for the administration of radioactive isotopes. For both diagnostic and therapeutic purposes, it is advantageous to use a method of administration that gives the greatest possible uniformity in rate of absorption of the injected isotope. When a

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