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Article
October 15, 1932

PHYSOSTIGMINE, A PERISTALTIC STIMULANT

JAMA. 1932;99(16):1329-1332. doi:10.1001/jama.1932.02740680025006
Abstract

About five years ago, at the suggestion of Dr. Soma Weiss, we began using physostigmine to increase gastric tonus and stimulate peristaltic activity.1 We found this drug to be of great value in the roentgen examination of the gastro-intestinal tract, and have used it with satisfactory results since that time. Our series now numbers over 1,200 patients and we deemed it of interest to report a summary of our observations in these cases.

Roentgenologists are familiar with the type of patient in whom the roentgen study of the stomach is made difficult if not impossible by the presence of a marked degree of atonicity, absent or sluggish peristalsis or spasm. In these instances, even after prolonged periods of fluoroscopic observation, it is often impossible to obtain satisfactory visualization of all portions of the stomach; or defects may be present without its being possible to determine whether they are due

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