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July 11, 1953


Author Affiliations

St: Louis
From the Department of Pediatrics, Washington University School of Medicine, and the St. Louis Children's Hospital.

JAMA. 1953;152(11):1028-1029. doi:10.1001/jama.1953.63690110001011

The rare observation of more than one person with leukemia in the same family has suggested this report. Acute leukemia affected each of fraternal twins during their second year of life. One twin died at the age of 18 months and the other at the age of 24 months.

REPORT OF CASES  Members of the family included the father, 29 years of age; mother, 32; a son, 9; three daughters, 8, 5, and 4; and the twin boys. The family lived in a small Illinois town. The twin boys, Terry and Jerry, were born Aug. 4, 1943. These twins did not resemble each other closely and were said, by the attending physician, to be fraternal and not identical twins. During pregnancy, the mother was said to have had toxemia with edema, albuminuria, and pyuria.Jerry weighed 5 lb. 8 oz. (2,494.8 gm.) at birth and gained weight regularly and satisfactorily.

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