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October 15, 1932


JAMA. 1932;99(16):1365. doi:10.1001/jama.1932.02740680061021

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Cause of Death in Intestinal Obstruction  Among the theories advanced in explanation of death due to intestinal obstruction, those most commonly defended are intoxication, infection, anhydremia and hypochloridemia. Hypochloridemia is today in favor owing to the surprising results often secured, in cases of intestinal obstruction, from hypodermic injections, or even lavages, of hypertonic solutions of sodium chloride. Dr. Bottin, in an experimental study published in the Revue de chirurgie, reviews the theories advanced thus far and shows that they are inadequte to explain the cause of death. If they play a part in the cause of death, it is only through a secondary action. Bottin ascribes the principal rôle to lesions of the pancreas. In support of this he cited the results of his experiments. He demonstrated that early ligation of the pancreatic ducts eliminates the grave phenomena and the lesions of the pancreas. The ligation appears to act by

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