We wish to call attention to the use of methoxamine hydrochloride (Vasoxyl)1 in the treatment of paroxysmal supraventricular tachycardia. Not only is this drug effective in arresting the tachycardia, but, because of its powerful pressor action,2 it is especially useful in cases complicated by vascular collapse, a frequent occurrence.3 The mechanism of action is believed to be a reflex vagal effect following carotid sinus pressure elevation. Two cases of paroxysmal supraventricular tachycardia complicated by vascular collapse, successfully treated by this agent, have been reported4 and two more are now added. The first case is one of nodal tachycardia and the second, one of auricular tachycardia.
REPORT OF CASES
C. M., a 63-year-old man, was admitted to the New Britain General Hospital on July 6, 1952, complaining of tachycardia of sudden onset, accompanied by dyspnea. He had previously experienced two similar attacks of tachycardia; the
Berger AJ, Rackliffe RL. TREATMENT OF PAROXYSMAL SUPRAVEN- VENTRICULAR TACHYCARDIA WITH METHOXAMINE. JAMA. 1953;152(12):1132–1133. doi:10.1001/jama.1953.63690120001012