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June 29, 1946

Current Comment

JAMA. 1946;131(9):746. doi:10.1001/jama.1946.02870260030012

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Abstract

EFFECTS OF THE COLD WAVE PROCESS  Recently The Journal published an article referring to cases of poisoning associated by the author with the use of thioglycolic acid in the so-called cold wave process for permanent waving of the hair. In this issue of The Journal Dr. Carey P. McCord calls attention to certain facts which he believes were overlooked by Dr. Lawrence H. Cotter in his discussion of the cold wave process. Dr. McCord is convinced that it is the hydrogen sulfide which constantly evaporates from thioglycolic acid that is primarily at fault and that it is possible by the use of certain chemical processes to inhibit the creation of hydrogen sulfide in sufficient amounts to be harmful. Dr. McCord believes that damage to the liver by the use of these chemicals has not yet been definitely shown in any instance. He believes that allergic responses are

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