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The author has written this book to provide a guide to help Australian practitioners, especially those in the country districts, who must rely for direction on hearsay, an odd article in a journal, or the brief direction of the advertising booklet. Beyond a few practical suggestions the author claims no originality for the content of the volume, although he has well reviewed such literature as is available to him. The first chapter deals with the history of rectal anesthesia, especially with ether, up to the recent introduction of "avertin," together with an explanation of fundamental physiologic effects of anesthetics given by rectum as compared with the effects when given by inhalation. The second chapter explains the chemistry and pharmacology of the drug, emphasizing its effect on the cardiovascular, respiratory and central nervous system. The author discusses the absorption, detoxication and excretion of the drug. A few words are written on
An Introduction to "Avertin" Rectal Anaesthesia.. JAMA. 1932;99(16):1378. doi:10.1001/jama.1932.02740680074037