[Skip to Content]
[Skip to Content Landing]
August 15, 1953


Author Affiliations

Pearl River, N. Y.; U. S. Army

From Viral and Rickettsial Research, Lederle Laboratories Division, American Cyanamid Company, Pearl River, N. Y., and the 130th Station Hospital, Heidelberg, Germany. Colonel Hoagland was formerly Chief, Medical Service, Station Hospital, U. S. Military Academy, West Point, N. Y.

JAMA. 1953;152(16):1527-1530. doi:10.1001/jama.1953.63690160002008a

In their work "Immunity in Mumps" Enders and his associates1 reported that persons having previously contacted mumps virus in the subclinical or clinical forms exhibited dermal hypersensitivity on intradermal inoculation of small amounts of heat-inactivated virus. These authors have found that, on the whole, this phenomenon correlated satisfactorily with a state of resistance against infection by mumps virus. They also proposed the following criteria for the interpretation of the skin reaction: an erythema of 10 mm. mean diameter or less should be considered to be a negative response; an erythema between 11 and 15 mm. in diameter should be considered a doubtful response; and an erythema over 15 mm. mean diameter should be regarded a positive reaction indicative of the resistant state. They used skin test antigens prepared from infected monkey parotid gland or from infected amniotic sacs with equally good results. Habel2 confirmed the observations of Enders

First Page Preview View Large
First page PDF preview
First page PDF preview