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August 22, 1953

RECURRENCE OF ULCER AFTER VAGOTOMY

Author Affiliations

Beverly Hills, Calif.; Long Beach, Calif.

From the medical and surgical services, Veterans Administration Hospital, Long Beach, Calif., and the University of California, Los Angeles.

JAMA. 1953;152(17):1593-1595. doi:10.1001/jama.1953.03690170007003
Abstract

Adequate therapy of duodenal ulcer should not only accomplish healing of the ulcer but should prevent its recurrence. Since the advent of vagotomy as a surgical treatment of duodenal ulcer the question of its effect on ulcer recurrence has been raised repeatedly. The literature on this subject is inadequate, and in most of the reports the data are inconclusive. For example, a report by Weber, Goldblum, and Gregg1 cites three cases of gastric ulceration following vagotomy. No insulin tests were done in two of these cases, and in the third case the insulin test would be considered by us to be inadequate, since the blood sugar level attained was only 58 mg. per hundred cubic centimeters. In addition, this patient had a gastroenterostomy, which in our experience frequently causes false negative results in insulin tests. Dragstedt2 states that persistence or recurrence of duodenal or gastrojejunal ulcer is almost

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