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August 31, 1946

Current Comment

JAMA. 1946;131(18):1502. doi:10.1001/jama.1946.02870350034010

ETHYLENE DISULPHONATE AND ALLERGY  The Journal has previously condemned1 the unfortunate publicity to the public concerning an early report2 on the use of a solution marketed under the name Ethylene Disulphonate by the Spicer-Gerhart Company of Pasadena and Sunland, Calif., for intramuscular injection in the treatment of a variety of allergic conditions. Elsewhere in this issue (p. 1495) appears a report of the Council on Pharmacy and Chemistry declaring Ethylene Disulphonate not accepttable for inclusion in New and Nonofficial Remedies. The report establishes that there is a reasonable doubt as to the existence of such a chemical compound as so-called ethylene disulphonate (ethylene disulphonic acid) with the hypothetical formula C2H2(SO3H)2. The report also indicates that the theory advanced by British and Belgian observers,3 on which the use of the product is presumably based by the American manufacturer is unproved and

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