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Article
September 12, 1953

CONGENITAL HEMOLYTIC ANEMIA IN NEGRO BROTHERSREPORT OF TWO CASES

Author Affiliations

Richmond, Va.

JAMA. 1953;153(2):103-104. doi:10.1001/jama.1953.02940190029007a
Abstract

Prior to 1944, there had been only one recorded instance of congenital hemolytic anemia in the Negro race. That was the case of a Negro woman of "undoubtedly mixed blood" cited by Wintrobe in 1942. In 1945, Scherer and Cecil reported the disease in a 14-year-old Negro girl, and Smith and Drake presented a 22-year-old Negro man. Both the man and the girl underwent splenectomy with good results. A review of the literature reveals that 15 other cases have been reported in the Negro race by various clinicians. In September, 1950, Butterworth, Kracke, and Riser reported two more cases, a woman and her great aunt. To date, a total of 18 cases in 9 families have been reported. Only 5 of the 18 patients had splenectomy, and it is interesting to note that only 4 of those 18 persons were Negro men.

The purpose of this paper is to present

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