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The author presents his investigations and findings in determining whether, in men, there is any connection between the morphologic sperm picture and pathologic changes in the testes.
The material examined was obtained from cadavers of 187 persons, aged 15 to 83 years, who died sudden, natural deaths or by accident, murder or suicide. Smears were secured from the epididymides. Testis sections were made at three different levels. In addition, testicular biopsies from 64 patients were also secured for comparison with the cadaver material.
The author's conclusions were about as follows: 1. No increase in the number of abnormal spermatozoal heads can be demonstrated with advancing age. 2. Persons with sterility problems possess more than 20 per cent abnormal spermatozoa. 3. It has not been possible to demonstrate any decline in the diameter of the tubules with advancing age or any greater extension of degenerative changes in the age group over
Morfologiske sperma- og testis-undersøgelser med særligt henblik paa forholdet mellem abnorm spermiemorfologi og forekomsten af patologiske forandringer I testiklerne. JAMA. 1950;142(5):378. doi:10.1001/jama.1950.02910230080038