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Except for the addition of new facts and late references, the second edition of Dr. Gaddum's textbook is nearly identical as to form and content with the earlier edition (1940). In the author's words this book is intended for "medical students at a stage in their education before general principles become obscured by a mass of practical details but may also interest others." It also attempts to present the evidence justifying the trial of new drugs when such trial is requested of medical men by manufacturers.
Included are the original twenty-two chapters of the first edition covering inorganic salts and fats, vitamins, hormones of known structure, hormones of unknown structure, central nervous system stimulants, narcotics, the brain (a chapter devoted essentially to the central nervous system depressants), other depressants of the central nervous system, body temperature, sensory nerves, motor nerve endings, muscles, the alimentary canal, circulation, blood, kidney, respiration, proteins,
Pharmacology. JAMA. 1946;132(2):114. doi:10.1001/jama.1946.02870370060030