[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.197.124.106. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Other Articles
May 27, 1939

NICOTINIC ACID IN THE TREATMENT OF ATYPICAL PSYCHOTIC STATESASSOCIATED WITH MALNUTRITION

Author Affiliations

AUGUSTA, GA.

From the Departments of Psychiatry and Internal Medicine, University of Georgia School of Medicine and the University Hosptal.

JAMA. 1939;112(21):2107-2110. doi:10.1001/jama.1939.02800210001001
Abstract

There have been reports of excellent results from the treatment of pellagrous psychoses with nicotinic acid;1 these have dealt with the more familiar mental symptoms occurring in frank or subclinical pellagra of the usual type. The present communication deals with observations made on nineteen individuals all presenting mental symptoms of somewhat similar pattern, none corresponding to the ordinary conception of pellagrous dementia. Hebetude grading into profound stupor was a feature so prominent that frontal lobe tumor was suspected in three patients, lethargic encephalitis in one and chronic subdural hematoma in a third. Delirium was present three times, agitated depression once, and one patient presented the signs of central neuritis. Signs of peripheral neuritis were not discovered, but five patients had marked deafness which disappeared under treatment; it was difficult to determine whether this transient deafness was due to failure of attention or to actual interference with the auditory mechanism.

First Page Preview View Large
First page PDF preview
First page PDF preview
×