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Article
October 5, 1946

Acetanilid: A Critical Bibliographic Review

JAMA. 1946;132(5):310. doi:10.1001/jama.1946.02870400058029

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Abstract

According to the author this monograph undertakes to review the voluminous literature on acetanilid in a critical fashion. The emphasis is placed on the reported toxicity of acetanilid, and the conclusion which appears to be reached is that this drug is much maligned. One might be willing to accept this conclusion at its face value if it weren't for two factors. The author appears to be extremely critical of all experimental and clinical work tending to show potential dangers from acetanilid, whereas he finds little fault with work tending to show the opposite. Secondly, the book was made possible by a grant from the Institute for the Study of Analgesic and Sedative Drugs, an institute founded and operated by members of the industry which promote acetanilid, aspirin, bromides and other sedatives and analgesics to the public. Nevertheless the book is valuable as a compilation of the literature on this drug,

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