Leukoplakia of the renal pelvis may be defined as the formation of pearly, opaque, firm plaques on the mucous membrane of that organ. The condition may be further defined as a metaplastic alteration of the cells lining that organ to cells of another type. Leukoplakia of the renal pelvis is a paradox. It simulates an epithelial process but occurs on a mucous membrane. Pathologically leukoplakia of the renal pelvis is of interest because of its uncertain causation and termination; clinically it is important because of its diagnosis and treatment.
Leukoplakia occurs on other mucous membranes of the body more frequently than it does in the renal pelvis. However, its occurrence in the renal pelvis may be considered uncommon but not rare. Rokitansky1 in 1861 first described leukoplakia of the bladder. It was not until 1882, twenty-one years later, that Ebstein first described leukoplakia of the renal pelvis. In a
McCREA LE. LEUKOPLAKIA OF THE RENAL PELVIS. JAMA. 1950;142(9):631–633. doi:10.1001/jama.1950.02910270021005