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November 7, 1953

VITAMIN B12 RESEARCH

JAMA. 1953;153(10):960. doi:10.1001/jama.1953.02940270066011

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Abstract

About 60 scientists representing government, university, hospital, and industrial laboratories recently met in Baltimore to participate in a symposium on current research in vitamin B12. The program, which was organized by Dr. Bacon F. Chow, associate professor of biochemistry in the School of Hygiene and Public Health of Johns Hopkins University, included reports on the metabolic roles of vitamin B12, the mechanism of its action in blood formation, and related subjects. During the two day conference, 20 investigators presented summaries of their data and conclusions on the various facets of the problems.

Evidence was presented that indicates an important role of the vitamin in the synthesis of nucleic acids and in the formation or function of such metabolically active compounds as glycine, serine, methionine, and choline. Interrelationships between vitamin B12, and other vitamins, such as pyridoxine and pantothenic acid, were demonstrated. Additional evidence for the interdependence of

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