January 9, 1954

Extrasystoles and Allied Arrhythmias

JAMA. 1954;154(2):184-185. doi:10.1001/jama.1954.02940360082032

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This monograph dealing with the manifestations, significance, therapy, and mechanisms of ectopic impulse formation in the heart is the result of extensive experimental and clinical studies of old as well as more recent data. Following a unique historical review of the development of knowledge about cardiac irregularities in general is a systematic description of the many varieties of premature beats and of disturbances of rhythm caused by them. Special chapters deal with fibrillation and flutter of auricles and ventricles, with paroxysmal tachycardia, and with alternans of the heart. An exhaustive discussion of the role of nervous factors and of drugs and electrolytes in the formation and suppression of ectopic beats is included. A final section is devoted to the authors' concept of the mechanisms of ectopic impulse formation.

The careful reader will find in this book an interesting mixture of a well-rounded presentation of generally accepted principles together with an

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