There is a mass of clinical evidence establishing the relationship between true cholecystitis and appendicitis. The research of Rosenow1 and the clinical observations of Heyd,2 Deaver,3 Mayo,4 Latham and English5 and Draper6 are examples of the attention this relationship has received in the literature. Rivers and Hartman7 found that 31.8 per cent of 879 patients operated on for true cholecystic disease had chronic or acute appendicitis, and Draper,6 more recently, found that 40.6 per cent of his patients with operative cholecystitis and cholelithiasis had concomitant appendicitis.
In view of the clinical relationship between cholecystitis and appendicitis, it has been supposed that a diseased appendix may be the cause of a reflex disturbance in the biliary tract. Dyskinesia of the gallbladder and the sphincter of Oddi is now a well established clinical entity. Oddi,8 Aschoff and Bacmeister9 and Berg10 were
CARTER RF, HOTZ R. REFLEX BILIARY DYSKINESIA RELIEVED BY APPENDECTOMYREPORT OF THREE CASES. JAMA. 1939;113(5):399-402. doi:10.1001/jama.1939.02800300029008