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February 20, 1954


Author Affiliations

Eloise, Mich.; Ann Arbor, Mich.

From the Atomic Energy Commission Laboratory on Biological Effects of Irradiation, the Michigan Memorial-Phoenix Project, University of Michigan, Ann Arbor, Mich., and the departments of pathology, University of Michigan, Ann Arbor, Wayne County General Hospital, Eloise, Mich., and Wayne University College of Medicine, Detroit.

JAMA. 1954;154(8):653-658. doi:10.1001/jama.1954.02940420015005

The effect of exposure of trichinous pork to gamma irradiation as a possible means of controlling the disease trichinosis in swine and man has occupied our attention during the past 18 months. By way of introduction, it might be well first to outline the cycle of trichinous infection. In man, trichinosis is contracted from ingestion of meat (nearly always pork) containing viable larvae of Trichinella spiralis. In hogs, the principal source of infection is trichinous pork eaten as scraps discarded from the kitchen. On ingestion of the infected meat, the muscle fibers and the cyst walls that enclose the parasites are digested, liberating the larvae. In the small intestine the larvae mature in three or four days to adult worms that then copulate. Toward the end of the first week, gravid females partially embedded in the mucosa of the intestine begin to give birth to young larvae of the second

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