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February 20, 1954


Author Affiliations


From the Department of Surgery, the Lahey Clinic.

JAMA. 1954;154(8):658-662. doi:10.1001/jama.1954.02940420020006

The intimate relationship between benign mucosal polyps and cancer of the colon and rectum (fig. 1) has been generally recognized, particularly by surgeons and pathologists who have had a special interest in this disease. Several general statements can be made that summarize this relationship. (1) Benign mucosal polyps of the rectum and colon occur in both sexes, slightly more commonly in males than in females, and at all ages. They occur with increasing frequency in the older age groups. (2) Polyps are frequently multiple and are found in our experience in approximately 25% of all surgical specimens removed for cancer of these organs. (3) There is a definite similarity between the age incidence and location of benign mucosal polyps and of malignant disease of the colon and rectum. (4) All stages between benign mucosal polyps and carcinoma of the colon and rectum can be demonstrated histologically. (5) Benign mucosal polyps

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