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Article
March 27, 1954

SYNDROME OF EPISODES OF HYPERSOMNIA, BULIMIA, AND ABNORMAL MENTAL STATES

Author Affiliations

New York

From the Department of Neurology, Columbia University College of Physicians and Surgeons, and the Neurological Institute of the Presbyterian Hospital of New York.

JAMA. 1954;154(13):1081-1083. doi:10.1001/jama.1954.02940470033008
Abstract

The episodic occurrence of states of excessive hunger (bulimia) and excessive sleep (hypersomnia) has been referred to as the Kleine-Levin syndrome by Critchley and Hoffman,1 by Ronald,2 and also by Palmer.3 In Kleine's4 series of five cases only two fit the syndrome to which his name later became attached, and it remains the merit of Levin5 to have clearly recognized the peculiar syndrome of "periodic somnolence and morbid hunger." Many of the case histories described in the literature (Kaplinskiy and Schulmann,6 Levin,5 Critchley and Hoffman,1 Ronald,2 and Palmer3) indicate that periodic somnolence and excessive hunger are not the only two features of the syndrome and that psychopathological phenomena should be added as the third component of the syndrome. Recent observers7 expressed the belief that the syndrome was confined to the male sex and the younger age group with onset

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