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June 24, 1950

INCLUSION BODIES DISEASE

JAMA. 1950;143(8):745-746. doi:10.1001/jama.1950.02910430037015
Abstract

Jesionek and Kiolemenoglou and Ribbert reported finding (1904) protozoon-like cells in the kidneys, lungs, liver and the parotid glands in isolated instances of stillborn infants. Goodpasture and Talbot described in 1921 similar cells in the lungs and kidneys of a child dying at 2 months of age with bronchopneumonia, traced their origin to altered tissue cells and drew attention to their resemblance to the affected cells in salivary gland disease of guinea pigs. Von Glahn and Pappenheimer reported in 1925 a case of intranuclear inclusions in the intestine, liver and lungsof a 36 year old man. Farber and Wolbach found 26 instances of inclusion bodies in 183 consecutive autopsies on infants less than 1/2 year of age. The inclusion bodies were confined to the salivary glands in 24 and were found in various viscera in 2.

McMillan1 reported a case of fatal inclusion disease pneumonitis in an adult, bringing

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