April 10, 1954

Jahresbericht 1950/51, Tuberkulose-Forschungsinstitut Borstel, Institut für experimentelle Biologie und Medizin

JAMA. 1954;154(15):1316-1317. doi:10.1001/jama.1954.02940490080031

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This important book contains summaries of two years' work by the large, competent, and diligent staff of the Borstel Tuberculosis Institute. Founded in the autumn of 1947, the institute is dedicated to the study of tuberculosis as a biological problem in man and animal. Bacteriologists, pathologists, clinicians, epidemiologists, veterinarians, pharmacologists, biochemists, physiologists, and roentgenologists are represented by fundamentally significant contributions in this volume, and these are in the form of objective research data, as distinguished from the familiar review with references.

Eight of the chapters report experiments in chemotherapy, especially with the thiosemicarbazones. Nine deal with the varied aspects of antibiotics, their persistence in the body, their excretion, their presence in normal saliva, and the production of an antituberculous substance by Escherichia coli. Here there is an especially remarkable chapter reporting a study on the distribution of antibiotics among higher plants, the oddities of this distribution within species and among

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