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July 1, 1950

Haemolytic Disease of the Newborn

JAMA. 1950;143(9):855. doi:10.1001/jama.1950.02910440073047

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"As an example both of serendipity and of the frequent coincident discoveries that are made in scientific fields, the discovery of the Rh antigen has rarely been equalled." With this introductory sentence Dr. Pickles presents a clear and well organized account of the rapidly advancing knowledge of Rh antigens and antibodies and effectively brings together the voluminous and confusing literature which has appeared in the last decade on this subject. The majority of physicians have insufficient knowledge of immunology and genetics, and this, together with the fact that the newer knowledge has come at a rapid pace and has sometimes been presented in a confusing manner, has led many to give up hope of ever understanding the subject. In this concise monograph Dr. Pickles has done a great service in putting together not only the theoretical aspects of the Rh problem but has also presented in a satisfactory manner the

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